Functional magnetic resonance imaging (fMRI) has come under skepticism from researchers questioning the validity of fMRI findings. The amygdala’s anatomical position makes robust fMRI mapping particularly difficult. Responses in the amygdala during emotional tasks was therefore particularly questioned.
We repeated runs of an emotional task during 7T fMRI and varied task instructions and technical factors.
In our recent Neuroimage publication, we provide important test metrics including reliability and systematic replicability. We conclude that high-resolution fMRI at 7T allows for robust mapping of amygdala activation.
Geissberger N & Tik M, Sladky R, Woletz M, Schuler AL, Willinger D, Windischberger C. Reproducibility of amygdala activation in facial emotion processing at 7T. Neuroimage. 2020 Jan 26:116585. 2020.